Career

Sano Postdoc

Project title: Computational Drug Repurposing: a Big Data Approach to Mouse Brain Atlas for Alzheimer’s Disease

Publication date: 07.12.2022

Closing date: 21.12.2022

Level of education: PhD

Hours: 40 hours per week

Salary indication: up to 14000 PLN gross monthly

Supervisor:

Sano: Dr. Ahmed Abdeen Hamed (Clinical Data Science collab between student and postdoc Leader)

Project period: project starts in 2023

Brain atlas are powerful tools for learning about Alzheimer’s and the discovery of potential treatment. Particularly, mice brain atlases are of great interest in the space of drug repurposing.

Our efforts specifically focused on analyzing the biomedical literature that is publicly available in PubMed Central. We used means of text analysis, ontology term extraction, network models and algorithms to identify drug candidates and rank them. The results were validated from relevant data collected from clinical trials records. Our research also observed the possibility of drugs being combined to achieve a treatment. The full description of such discoveries is published in the JMIR and Pharmaceutics journals. Such analysis can enable the exploration of multiple layers of drugs, genes, proteins, cells, and compare it against various mouse strains.

This project strives to test the potency of drugs combinations on the brain of various model organisms.  Therefore, this project aims at the development of a multilayer mouse brain atlas as an exploratory tool to illuminate insights that could favor the treatment of Alzheimer's.

The main activities planned within this project involve the following:

•     Performing literature reviews for the state-of-the-art

•     Participate in planning, designing, architecting, testing the various development phases of the atlas

•     Perform lab test for the drug candidates that identified (in-vivo/in-vitro if needed and possible)

•     Perform data analysis, vetting, and plotting, and visualizing

•     Participate in a pair-programming activities (even without being familiar with programming)

This project is planned as a collaborative multi-institute, multidisciplinary that includes PhD students, Postdoctoral, and scientists from across the world.

Sano Postdoc

Project title: Strengthening patient and physician confidence in artificial intelligence diagnoses and recommendations

Publication date: 1.12.2022

Closing date: 15.12.2022

Level of education: PhD

Hours: 40 hours per week

Salary indication: up to 14000 PLN gross monthly

Supervisor:

Sano: Dr. Przemysław Korzeniowski (Health Informatics Team Leader)

Project period: 1 - 2 years

A Post-doctoral project in the field of the human-computer interaction is focused on trust in Artificial Intelligence (AI) systems in healthcare. The project aims to experimentally verify whether physicians are willing to collaborate with the AI system on a diagnosis and to discover factors increasing physicians' trust in AI. The second goal is to develop such virtual settings in which patients' well-being is flourish during the AI diagnosis process. 

Sano presents a great opportunity for people who want to make a change in the world by developing life-changing technologies and solutions for healthcare worldwide.

We are looking for a:

Copywriter – part-time (1/2 FTE)

Sano is in the phase of rapid growth and we are looking for a person willing to strengthen our Development team and help in building Sano’s online presence.

Sano Postdoc

Project title: Postdoctoral Fellowship in Cheminformatics

Publication date: 25.11.2022

Closing date: 20.12.2022

Level of education: PhD

Hours: 40 hours per week

Salary indication: up to 14000 PLN gross monthly

Supervisor:

Sano: Dr. Ahmed Abdeen Hamed (Clinical Data Science team leader)

Project period: Jan 2023

The position is for Sano's Clinical Data Science team. Our group develops a new generation of semantically integrated databases for clinical and biomedical. Our system will build on recent Big Data workflow technologies to integrate using a multitude of very large data sets, including text mining results, mutation databases, internal and external -omics high-throughput sets, ontologies, and clinical data.  

Clinical Data Science group is seeking a creative and self-motivated cheminformatician with exceptional interpersonal and problem solving skills to join the team.

Sano PhD Student

Project title: The Role of Neurocardiac Interaction in Arrhythmic Digital Twin Hearts

Publication date: 25.11.2022

Closing date: 20.12 2022

Level of education required: Master's degree

Hours: 40 hours per week

Salary indication: up to PLN 8000 gross monthly

Supervisors:

Sano: Dr Maciej Malawski (Extreme Scale Data and Computing Research Group Leader)

University of Sheffield: Dr. Ian Halliday

Project start: Jan 2023

Degree Awarding Body: University of Sheffield

The primary question to be addressed in this project is whether neurocardiac interaction at both Autonomic Nervous System (ANS) level and Intrinsic Cardiac Nervous System (ICNS) level can be incorporated in digital cohort/twin models of the whole human heart, in particular those developing arrhythmias. If so, how are we to approach this in Digital Twin models, given sparse information about both the ANS and ICNS at an individual patient level.

Understanding the role that the ICNS plays in controlling cardiac function, and how it interacts with information between the central command centres of the ANS and integrates sensory information from the myocardium could prove crucial for prophylactic and corrective treatments of heart disease. In particular, clusters of cardiac ganglia neurons located on the surface of the heart, collectively termed ganglionated plexuses (GP), are known to be involved in arrhythmias. An array of imaging, modelling and simulation studies should be devised to address the question of whether Digital Twin Heart modelling can incorporate and will benefit from ANS and ICNS control insights. In particular, can we incorporate knowledge of the structure and function of the Intrinsic Nervous System to provide better modelling of arrhythmias? Further, can this knowledge be used to provide guidance in (optimal) ablation of the ganglionated plexuses?

Sano Postdoc

Project title: Postdoctoral fellowship in Neuroimaging

Publication date: 11.10.2022

Closing date: 11.11.2022

Level of education: PhD

Hours: 40 hours per week

Salary indication: up to 14000 PLN gross monthly

Supervisor:

Sano: Dr. Alessandro Crimi (Research Group Leader)

Project period: Contract until the end of 2023 with an option to extend.

BrainAndMore (BAM) lab focuses cutting edge genetic, molecular and mainly magnetic resonance imaging technology to understand diseases and support drug development efforts in the neuroscience field.

In this project you will be working on machine learning approaches for neuroimaging. From segmentation of vessel structures in brain data to more advanced tasks, ranging from data analysis of mice brain data to MRI of humans. According to the inclination of the applicant we can reshape towards more specific data and research questions.

This project will be carried out in cooperation with machine learning and AI scientists at Sano and its partners and by developing external collaborations in France and across Poland.

In this project we want to investigate different types of neuroimaging beyond connectomes, by using both structural and functional data.

Sano PhD Student

Project title: PhD Student position in Neuroimaging

Publication date: 11.10.2022

Closing date: 11.11.2022

Level of education: MSc

Hours: 40 hours per week

Salary indication: up to 8000 PLN gross monthly

Supervisor:

Sano: Dr. Alessandro Crimi (Research Group Leader)

Project period: 4 years

BrainAndMore (BAM) lab focuses cutting edge genetic, molecular and mainly magnetic resonance imaging technology to understand diseases and support drug development efforts in the neuroscience field.

In this project you will be working on machine learning approaches for neuroimaging. From segmentation of vessel structures in brain data to more advanced tasks, ranging from data analysis of mice brain data to MRI of humans. According to the inclination of the applicant we can reshape towards more specific data and research questions.

This project will be carried out in cooperation with machine learning and AI scientists at Sano and its partners and by developing external collaborations in France and across Poland.

In this project we want to investigate different types of neuroimaging beyond connectomes, by using both structural and functional data.

Sano presents a great opportunity for people who want to make a change by developing solutions for healthcare and wellbeing.

We are looking for an experienced:

 Scientific Developer in Machine learning applied to neuroimaging and VR/AR

You will help turn scientific vision into tangible solutions for clinicians and patients. Your high-quality code will propel new healthcare products, for improvement treatment and wellbeing of citizens in Poland and abroad. You will work with Sano’s researchers and clinical collaborators to bring Sano’s technology to hospitals and patients.

We invite you to join a team of professionals at the core of a new, fully independent research institute. Our common task will be to assist, to the best of our abilities, excellent Sano researchers in bringing their novel solutions to healthcare industry, hospitals, doctors, and patients. We will do that by setting high standards of software development and data management, where no corners are cut, and the patient’s benefit is the ultimate goal.

The project might eventually develop into a spin-off startup, where you will continue to be the driving force.

Sano presents a great opportunity for people who want to make a change by developing solutions for healthcare and wellbeing.

We are looking for an experienced:

 Kotlin Developer – Scientific Programmer

You will help turn scientific vision into tangible solutions for clinicians and patients. Your high-quality code will propel new healthcare products, for improvement treatment and wellbeing of citizens in Poland and abroad. You will work with Sano’s researchers and clinical collaborators to bring Sano’s technology to hospitals and patients.

We invite you to join a team of professionals at the core of a new, fully independent research institute. Our common task will be to assist, to the best of our abilities, excellent Sano researchers in bringing their novel solutions to healthcare industry, hospitals, doctors, and patients. We will do that by setting high standards of software development and data management, where no corners are cut, and the patient’s benefit is the ultimate goal.

We are looking for a:

Finance Specialist

As a member of the Sano financial team you will help with the key financial processes by coordinating the work-flow of important documents, monitoring the implementation of budgets continuous assistance with everyday financial tasks.

You will work in an international environment and you will be responsible for the coordination of distribution of financial data between different departments. You will be assisting Sano employees in preparing necessary financial documentation.

You will work in a fast-growing research organization, so you need to be open to continuous development and professional challenges.